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More than 13 000 laboratory-confirmed mpox cases have been reported in the African region since the start of 2024, as of 17 November. Three countries – Burundi, the Democratic Republic of Congo and Uganda - account for approximately 97% of all reported cases so far this year. From reinforcing outbreak control measures including health worker training, to the delivery of medical supplies and equipment, and to the development of vaccine deployment plans, World Health Organization (WHO) is providing critical technical and financial support to countries to effectively respond to and end the mpox outbreaks in the region.

The Democratic Republic of the Congo is the hardest hit country in the African region by mpox outbreak, accounting for about 80% of laboratory-confirmed cases and deaths reported across the continent this year. While mpox is primarily transmitted through close physical contact, it can affect anyone. Vulnerable populations are at a heightened risk of infection and severe illness.

Despite notable strides made in African countries, an accelerated response to the burgeoning threat of antimicrobial resistance (AMR) is critical to avert predictions of 4.1 million related deaths annually by 2050, with severe consequences for health care and economic stability.