The U.S. Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO) have a longstanding and strong partnership in Africa, consisting of technical and financial collaboration. To enhance their strategic cooperation on HIV/AIDS, WHO and CDC conducted a multi-country grant implementation and strategic review meeting on 9-11 March 2015 in Addis Ababa. CDC and WHO staff from Headquarters and Regional Offices, as well as the country offices of Cameroon, Ethiopia, Namibia, South Africa and Uganda, took part in the meeting.