The government of Zanzibar recently endorsed tobacco control regulations in line with the Public and Environmental Health Act on 2012. These regulations are aligned to the provisions of the WHO Framework Convention on Tobacco Control (WHO FCTC). The WHO FCTC is the world’s most powerful tool to tackle the escalating epidemic of tobacco use and exposure to tobacco smoke and their negative impact on health, social and economic development. The FCTC sets out strategies that will lead to tobacco demand reduction and supply reduction while at the same time providing for international cooperation and monitoring of trends in the tobacco epidemic. These measures aim at reducing tobacco use while at the same time protecting non-smokers from second hand smoke.