Public health emergencies in the African Region present a complex and multifaceted challenge that demands a comprehensive and collaborative response. The Region carries the highest burden of public health emergencies globally, with over 100 major events reported each year.

Four technical clusters namely Family Health, Health Systems, Communicable Diseases and Noncommunicable Diseases fall under programme management. In addition two cross cutting programmes, Health Promotion and Social and Economic Determinants; and Planning, Budgeting, Monitoring and Evaluation report directly to Programme Management.