Universal access to Sexual and Reproductive Health and Rights (SRHR) is one of the key components of the Sustainable Development Goals (SDGs) 3 and 5 and contributes to the achievement of all the other SDGs. Given its critical roles therefore, WHO/AFRO is implementing a new four-year initiative, launched on 9 January 2019, to enhance existing efforts for reducing needless deaths from pregnancy in the region focusing on the provision of comprehensive Sexual and Reproductive Health and Rights (SRHR) services, within the Universal Health Coverage (UHC) framework, especially for the most vulnerable populations, including those living in humanitarian settings.