Polio is a highly infectious, debilitating disease which affects children and causes permanent paralysis. Polio is not curable, and can only be prevented by vaccination. Families and communities must ensure their children are vaccinated both during polio campaigns and through routine immunization. The Horn of Africa is currently in emergency with imported poliovirus of circulating vaccine derived polioviruses placing polio eradication as unfinished business. Circulating vaccine Derived-Polio Virus (cVDPV) outbreak was reported recently from Somaliland and the first-round quick response has been conducted in July 2019. Since then four more cases have been reported in Puntland in Somalia, one in Bosaso district, one in Ufyan district, one on the border with Somali region in Ethiopia and one in Dollo Zone Bokh Wareda in Somali Region of Ethiopia.